منابع مشابه
Spatial distribution of white-matter hyperintensities in Alzheimer disease, cerebral amyloid angiopathy, and healthy aging.
BACKGROUND AND PURPOSE White-matter hyperintensities (WMHs) detected by magnetic resonance imaging are thought to represent the effects of cerebral small-vessel disease and neurodegenerative changes. We sought to determine whether the spatial distribution of WMHs discriminates between different disease groups and healthy aging individuals and whether these distributions are related to local cer...
متن کاملRole of aerobic fitness and aging on cerebral white matter integrity.
Neuroimaging research suggests that cerebral white matter (WM) integrity, as reflected in fractional anisotropy (FA) via diffusion tensor imaging (DTI), is decreased in older adults, especially in the prefrontal regions of the brain. Behavioral investigations of cognitive functioning suggest that some aspects of cognition may be better preserved in older adults who possess higher levels of aero...
متن کاملCerebral white matter lesions, retinopathy, and stroke.
and Stroke To the Editor: I read with interest the study by Vermeer and colleagues1 on the risk of stroke associated with MRI-defined white matter lesions (WML) in the Rotterdam Scan Study. As cerebral MRI becomes a routine diagnostic test for widening indications of neurological disorders, this study provides further data on the clinical significance of these lesions in asymptomatic elderly pe...
متن کاملCerebral white matter deficiencies in pedophilic men.
The present investigation sought to identify which brain regions distinguish pedophilic from nonpedophilic men, using unbiased, automated analyses of the whole brain. T1-weighted magnetic resonance images (MRIs) were acquired from men who demonstrated illegal or clinically significant sexual behaviors or interests (n = 65) and from men who had histories of nonsexual offenses but no sexual offen...
متن کاملAdrenomedullin Deficiency and Aging Exacerbate Ischemic White Matter Injury after Prolonged Cerebral Hypoperfusion in Mice
Adrenomedullin was originally isolated from pheochromocytoma cells and reduces insulin resistance by decreasing oxidative stress. White matter lesions induced by aging and hyperglycemia play a crucial role in cognitive impairment in poststroke patients. Here, we examine whether adrenomedullin deficiency and aging exacerbate ischemic white matter injury after prolonged cerebral hypoperfusion. Ad...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Ageing Research Reviews
سال: 2017
ISSN: 1568-1637
DOI: 10.1016/j.arr.2016.11.006